This week, we heavily
discussed the nature of addiction and depression, which made me compare and
contrast the impacts of addiction and depression as one unit. Often, depression
is treating with antidepressants, but to what degree do they actually work?
And, to what degree to they promote an inclination to addiction? Oddly enough,
I wasn’t the first to think of this correlation.
From a government study conducted (though about ten
years ago), it was found that antidepressant have not really been improving in their
ability to combat depression, but rather to reduce the side effects of previous
antidepressants. This in turn begs the question: what is the cause of
depression? The answer? Too many. Yet, doctors and scientists continue to
invest effort to discover new drugs to prescribe in an ongoing effort to cure
this “illness”. Steven Hyman, director
of the National Institute of Mental Health, explains how there is a related
link between cortisol levels and levels of depression. This causal link
highlights how depressed individuals may have increased alertness, but lower
sexual drive and appetite. So, block the hypothalamic-pituitary-adrenal (HPA)
pathway that pumps out the cortisol and yay, problem solved! If only.
It has to of course be more complicated. Mental
health is the key in understanding depression and any potential antidepressant
addiction that accompanies it. The role of the mind has been witnessed through
Placebo effects and withdrawal symptoms of taking or stopping antidepressants. For
instance, “35% of placebo patients typically improve” compared to the 50% that
typically notice results when taking the actual drug. And often time,
differences between the two prove to be statistically insignificant. Can the placebo be the cure? I feel these studies emphasize the inevitability of mental health being in
charge of one’s depression. This being the case, it is easy to assume that an
individual can develop a mental addiction to antidepressants based on the
notion that it is the only cure for them and without it they are unable to
thrive. Harvard Health discusses going off antidepressants as an alignment with discontinuation symptoms. There are key differences to
note between a depressed individual’s depression symptoms and discontinuation
symptoms. The SRIs, serotonin-norepinephrine reuptake inhibitors contribute to
withdrawal symptoms. Poor positive framing increase these symptoms; based on
our discussion in class, withdrawal symptoms, if disrupting day to day order or
forcing an individual to seek drugs for relief no matter what, can be characterized as an addiction.
However the mind, body, and soul work together, I do
respect nature’s path. If depression is an evolutionarily adapted trait, the
difficulty found in “curing” depression might be nature’s way of hinting that
it shouldn’t be treated as an illness nor should the existence of it be
abolished. Humans have been living for thousands of years, and if signs of
depression have assisted in that travel, then perhaps there is some beneficial
purpose to it after all.
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